Hi L Shaffer,
If you were tax resident in the UK at the time you disposed of your US property, you will need to declare the gain in a self assessment tax return and claim a foreign tax credit for up to 100% of the US tax paid.
All parts of your UK capital gains calculation must be in pounds sterling, using a just and reasonable exchange rate in use at the time of acquisition and disposal.
Private Residience Relief, can be claimed for the period that the property was your main residence and can be set against the capital gain.
Have a look here:
HS283 Private Residence Relief (2023).
There is also a calculator here:
Tax when you sell property
Which you can use to help work out the taxable gain.
Thank you.